Larvol Cliniclarvol.hashnode.devยทSep 20, 2024Single-Cell DNA Sequencing Reveals Clonal Dynamics in FLT3-Mutated Acute Myeloid Leukemia during Crenolanib Combination TherapyBackgroundSingle cell RNA (scRNA) sequencing analysis suggests that the presence of FLT3-ITD mutation is associated with a progenitor-like phenotype (1van Galen, et al. Cell, 2019: 176, 1265) while activating mutations in the FLT3 kinase domain are a...TumorAdd a thoughtful commentNo comments yetBe the first to start the conversation.
