Larvol Cliniclarvol.hashnode.dev·Jul 18, 2024Phase Ib/II Study of Lacnotuzumab in Combination with Spartalizumab in Patients with Advanced MalignanciesAbstract Introduction: Blocking the colony-stimulating factor 1 (CSF-1) signal on tumor-associated macrophages can lead to an upregulation of checkpoint molecules, such as programmed cell death ligand 1 (PD-L1), thus causing resistance to this blocka...CancerAdd a thoughtful commentNo comments yetBe the first to start the conversation.