Larvol Cliniclarvol.hashnode.dev·Jul 26, 2024Randomized phase II stereotactic ablative radiation therapy (SABR) for metastatic unresected renal cell carcinomaThis project was supported by grants U10CA180822 (NRG Oncology SDMC), U24CA196067 (NRG Specimen Bank), U10CA180868 (NRG Oncology Operations), U24CA180803 (IROC) from the National Cancer Institute (NCI).” Background:The treatment landscape for patient...Discusshealthcare
Larvol Cliniclarvol.hashnode.dev·Jul 26, 2024Belantamab Mafodotin Exhibits No Evidence Of Immune Cell ImpairmentTopic: Myeloma and other monoclonal gammopathies — Biology & translational research Background:Belantamab mafodotin (belamaf) is a B-cell maturation antigen (BCMA) targeted antibody-drug-conjugatewith mechanisms of action against multiple myeloma (MM...Discussindia
Larvol Cliniclarvol.hashnode.dev·Jul 18, 2024An Investigational Study of Immunotherapy Combinations in Participants With Solid Cancers That Are Advanced or Have SpreadBrief Summary The purpose of this study is to demonstrate the safety and preliminary activity with triple combinations of relatlimab in combination with nivolumab and BMS-986205, or in combination with nivolumab and ipilimumab in immunotherapy-naive ...DiscussGoogle
Larvol Cliniclarvol.hashnode.dev·Jul 18, 2024TLR agonists polarize interferon responses in conjunction with dendritic cell vaccination in malignant glioma: a randomized phase II TrialAbstract In this randomized phase II clinical trial, we evaluated the effectiveness of adding the TLR agonists, poly-ICLC or resiquimod, to autologous tumor lysate-pulsed dendritic cell (ATL-DC) vaccination in patients with newly-diagnosed or recurre...Discussindia
Larvol Cliniclarvol.hashnode.dev·Jul 18, 2024Phase Ib/II Study of Lacnotuzumab in Combination with Spartalizumab in Patients with Advanced MalignanciesAbstract Introduction: Blocking the colony-stimulating factor 1 (CSF-1) signal on tumor-associated macrophages can lead to an upregulation of checkpoint molecules, such as programmed cell death ligand 1 (PD-L1), thus causing resistance to this blocka...DiscussCancer
Larvol Cliniclarvol.hashnode.dev·Jun 28, 2024Reducing Urban Cervical Cancer DisparitiesStudy Overview Brief Summary This study uses a hybrid Type 1 effectiveness-implementation trial to operationalize and assess the efficacy of the Health Enhancement Resource System (HERS) intervention. HERS aims to increase patient follow-up after abn...DiscussGoogle
Larvol Cliniclarvol.hashnode.dev·Jun 21, 2024Dalpiciclib and chidamide in patients with HR+/HER2- advanced breast cancer and resistance to CDK4/6 inhibitors: A phase Ib trialBackground:The combination of CDK4/6 inhibitors and endocrine therapy (ET) as first or second-line therapy could improve PFS and OS for patients with HR-positive/HER2-negative breast cancer. However, the standard treatment for patients who have faile...DiscussGoogle
Darko Medindarkodatasci.hashnode.dev·Jan 30, 2023Biostatistics & AI/ Machine Learning / Light Gradient Boosting Machine Model for Gene expression data. Cancer type Classifier.In this exemplary project, Cell line Expression atlas Gene expression data is used to create a state-of-the-art Machine learning model to classify leukemia and separate it from the other types of Cancer. You may find the code and additional data on t...Discuss·2 likes·480 readsbioinformatics
