My first program was in BASIC, it was reversing the letters in a word.

In my opinion you should think about what you want to achieve. Do you want to create an engine yourself as a foundation for your game or do you want to focus more on creating the game itself and not worry so much about render pipelines and other complex engine stuff? If you are already familiar with C# then you should feel "at home" with Unity.

Small correction, MVC comes from Model, View, Controller.

You should check out Angular-CLI, it creates a new Angular 4 project that handles out of the box: a local development server with live reload automatic transpile of typescript to es5 minification lazy loading of modules and bundling it generates unit test files for your components you can use LESS/SASS files instead of CSS You should really give it a try, it took me a whole day to get used to the build system and Typescript but now I think I'm in love with these features :)

It is considered bad practice to use jquery with angular. jQuery takes a traditional imperative approach to manipulating the DOM, and in an imperative approach, it is up to the programmer to express the individual steps leading up to the desired outcome. AngularJS, however, takes a declarative approach to DOM manipulation. Here, instead of worrying about all of the step by step details regarding how to do the desired outcome, we are just declaring what we want and AngularJS worries about the rest, taking care of everything for us.

This is exactly like the one I had when I was a little kid :D awesome!

This is not quite accurate as $onChanges is not available in 1.5 but in 1.5.3.