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Flat 10% Off Use Code "SALE10", Free Shipping In USA Tapentadol is a medication that is primarily used for the management of moderate to severe pain. It is an opioid analgesic, which means it works by binding to opioid receptors in the brain and spinal cord to reduce the perception of pain. Tapentadol is often prescribed when other pain medications, such as non-opioid analgesics or weaker opioids, are not sufficient for controlling pain.