Yes! And I'm loving it so far.
As a full stack software engineer, I do use Typescript for frontend with React. And for backend, I used it with express, serverless cloud functions, and nextjs. It's great!
If you are interested in learning Typescript and static types, I wrote a long-format article about how to think in TS: A Mental Model to think in Typescript .
And I'm also doing a series on TS Learnings: Typescript Learnings Series