There is Loopback and Strongloop.
Strongloop is the name of the company and a tool collection for Loopback (including the scaffolding tool and the PM).
Loopback is a big webserver and REST/API framework with a big ecosystem around the actual framework (ProcessManager, GUI, ORM). It brings a lot "ready to use". Like autorization, authentification and usermodels.
It's only backend. The frontend is still yours.
I tried it but actualy don't use it. The docs and the tutorial within them helped me a lot to get started.