Check out the following discussions :

• Prashant's answer to "Best Resources for learning React"
• Where to start with React
• Trickiest parts of React

5 Steps for learning React is a must read. Especially step 1, understand why facebook built react. It's very insightful.

Petehunt's react-howto it's a nice start point.

1. learning how to use webpack and setup a project

2. learning something use redux firstly(shows the best practice use reat js correctly). ---- egghead.io/series/getting-started-with-redux

3. then use MERN as prototype(boot your prototype in some minutes).

4. learning Material-UI if you need polish your webapp That is all.

Learn how to build Todolist in React first. It's a basis of building larger apps: github.com/tastejs/todomvc/tree/gh-pages/examples…

Remember to checkout Elm(http://elm-lang.org/). The idea behind React called Flux(and Redux) learnt a lot from functional programming community and Elm is one of them. It helps in building very large projects.