When you install Node.js, it comes with a REPL.
Type node in your console and the Node REPL starts or read more about it.
Not sure how it compares to iPython because I never used iPython.
I'm sure about what you are looking for, but in Jupyter (also known Ipython) it's possible to change the Kernel for the specific language you want. Take a look at this package for the JS Kernel: https://www.npmjs.com/package/ijavascript
Andreas Biørn-Hansen
React (Native) Enthusiast
What about Nancy? Haven't tried iPython so I can't compare, though.