Discussion on "文獻摘要: Measurement of cyclosporin induced changes in P glycoprotein function at the human blood brain barrier using 18F MC225 and PET"

Aldo Yang · 2025-05-11T04:42:06.206Z

Objectives 驗證 [18F]MC225 作為一種特定的 P-glycoprotein (P-gp) PET 顯影劑，可用於使用 cyclosporin 作為抑制劑，在活體人體 blood-brain barrier (BBB) 測量 P-gp 功能的變化。顯示在給予 cyclosporin 後，[18F]MC225 在全腦 grey matter 的 volume of distribution (VT) 顯著增加，反映了 P-gp 的抑制。顯示 [18F]MC225 對於研究 ...

Discussion on "文獻摘要: Measurement of cyclosporin induced changes in P glycoprotein function at the human blood brain barrier using 18F MC225 and PET" | Hashnode

Search Hashnode

文獻摘要: Measurement of cyclosporin induced changes in P glycoprotein function at the human blood brain barrier using 18F MC225 and PET

Responses