To deploy your Django REST framework and React application to production, you'll need to host it on a server. Services like Heroku, AWS, or DigitalOcean can help with this. You'll set up a server, configure your Django backend with a web server like Gunicorn, and serve your React frontend. You'll also need to handle static files and set environment variables for things like database credentials. For detailed instructions, check out the documentation or tutorials specific to the hosting service you choose.