When is a good time to apply for jobs in Startups?

I am graduating Apr/May 2019 and I wonder when should I start my job search? I mainly work on frontend technologies with two internships being in the Front End Domain, but I have worked with Node in my side projects. I hear this advice of "apply ear...

Why is front end development complex? Why do you like it? If you are a full stack developer which side(front end or backend) do you lean more?