Yes at least for me and I'm in the process, I'm doing it due to partially child care but also because I have certain traits which are undesired and to be honest its the only option left that I can think of if i want a successful future for me and my daughter, a house paid in full and a business to leave behind :)
I did once before so I've always had the initiative but I suppose it can be down to insecurity's thinking will you make it, can be a stall on any kind of progress and in return you just have to keep believing in your self that you will make it and carry it all through :)
If you have a passion and you think you've got something then go a head :)