Hmm, TypeScript is a cool option but at the moment i am mostly focused on ES6 / ES7 coding.
In my mind all front end developers, no matter what js framework they mostly use (Angular, Ember, Vue, React, Polymer and so on), should definitely master ES6 / ES7 first. This is the basic ingredient. It is the language itself that evolves so we have to master it right?
I have seen some developers who went right away from ES5 to TypeScript because it was easier to write code in Angular 2 that way. Yes i agree with them. It is easier, faster etc But this is a bad decision in my mind.
My answer is "One step at a time". If you feel comfortable enough in using the new standards then you should go for TypeScript but don't push things that way, it is wrong.