It depends. Now we can see a lot of optimistic articles about HTTP/2, for example the following: How HTTP/2 Can Speed Up Your Site
But there a also many conditions, when http/2 won't provide a significat profit for your website HTTP/2 arrives but sprite sets ain’t no dead
As for me .. I don't use png sprites any more last 2 years, and had replaced them with svg sprites (symbol/use technique)