Yes, as always after useless experiments and overengineering people will, of course, use something:
That why jQuery was so popular and lived for 10+ years while all your so called modern "frameworks" come and change every year.
And actually I already started solving this #1 modern front-end problem.
If you love vanilla JS and tired of learning useless frameworks, you just want to import X and everything works like it was with jQuery and jQuery UI then please star https://bunnyjs.com, share your feedback, contribute!
Add me on Twitter or Facebook /mevrael, I will answer all your questions and will teach you simple JS itself and absolutely for free.