10 years is a bit too far for making good predictions (for instance, 10 years ago was 2007, not even AngularJS v1 existed!).
I can tell at least that in 3 years, JavaScript will gain more the status of a VM and lose the status of a language. Already today, not many people use raw JavaScript. You usually have some transpilation, at least e.g. Babel. In the future, Web Assembly will enable more innovation in that regards, and existing transpiling languages like Elm, TypeScript, PureScript will continue to improve.