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I would start by following known ARIA patterns which are rooted in years of user research and best practice. This link has information on modal and non-modal dialogs: http://w3c.github.io/aria-practices/

Following best practices can give you a solid baseline for accessible components. But it is also very useful to do user testing with people with disabilities on your own application to get feedback on a particular thing you've created. Access Works at Knowbility is one organization that can help you find usability test subjects: http://www.access-works.knowbility.org/