When I have to, such as on legacy sites/apps that still use it, but on new projects where React/Angular are overkill, I use native browser APIs and microlibraries. So typically this means document.querySelectorAll() and an Ajax library like superagent or fetch. I don't think jQuery is needed at all anymore unless you need old IE support or are working with developers that don't want to learn new APIs/syntax (there are still nice lightweight replacements for jQuery with same syntax for DOM).