Honestly it's going to depend on your physiology. Ergonomic furniture is generally made for 95% of the population. I have a long torso so I usually don't fit comfortably in ergonomic furniture. The best ergonomic furniture is fully adjustable everywhere but that doesn't necessarily make it comfortable. Something which is soft and cushy to me is preferable to a mesh plastic "ergonomic" chair. A comfy chair is a comfy chair, regardless of whether or not it's "ergonomic".
Before you buy a new chair you should find someone with a standing desk you can try out. I love mine. I stand at work and sit at home. The variety has helped my back pain.