This is one of those questions that depends pretty heavily on the browsers you need to support. If you only need to support the evergreens, you probably don't need jquery (or as the site says, YMNNJ http://youmightnotneedjquery.com).
Also if you work on an established product that can't work without jQuery, you might find it's not worth the overhead. More so if you work with other people who haven't learned ES6 yet.