I love jQuery and 5 years ago I couldn't imagine any web app without jQuery. But today is different - JS, HTML and CSS has evolved a lot, and new frameworks have emerged to solve different needs. Right now I'm working on a SPA web app without jQuery and, surprisingly, I'm not missing it at all.
jQuery is fantastic for DOM manipulation, but IMO, as development in client side became more complex, the need for a more rubust, modularised and flow-control has grown up, and the core jQuery can't help much on that.
If I had to bet on the next 10 years, I'd say that this jQuery we know will just support legacy apps.