Are there any co-working spaces around you? If your main concern is being lonely perhaps find a place where you can work among other developers. I guess it depends on your area and what kind of contact you desire.

I don't think anyone else can answer this for you. It's about what you value more.

But I'll note that it's not as black and white as that:

• There are probably other differences between the jobs: bigger companies have more job security but also bureaucracy, you'll be more specialized but have less individual impact, technologies are different and some companies have more helpful culture.
• These two jobs aren't the only choices, maybe with some time you can find a higher pay position that isn't remote, if that's what you want.
• While colleagues are not around you, you can have regular contact working remotely (depending on the job).