Not really different languages, but yeah , If I am familiar with angular, I will try and use React, mobx instead of redux, bulma instead of bootstrap/foundations etc..

Yes I have. In fact, that is what got me to hashnode. But I found it too complex to understand. I first need to figure out exactly how do all the parts work in an isomorphic app especially using this stack ( this is the first time I am trying to create an isomorphic app). Then may be I can use MERN for kickstarting my projects with confidence.

This is not isomorphic/server side rendered. That is my primary requirement right now. Was able to setup my own boilerplate , but without isomorphic behaviour.