I cannot imagine browsing the Internet without an ad blocker. At first, I used AdBlocker, but eventually I changed it to uBlock. There were some speculations that the original uBlock source code for Chrome was sold to advertisers and was manipulated. That's how the uBlock Origin was born. Why I've migrated to uBlock you may ask - it's faster than AdBlocker, at least in Chrome.
Some sites are blocking the adblocker scripts, so I'm using an anti-adblocker. The source code can be found here - github.com/reek/anti-adblock-killer.
I also use the easyprivacy/disconnect list in combination with Disconnect, which can be an overkill, but I've never took the time to see if they overlap. Nevertheless, I'm pretty happy with the setup I have.