Easy, I don't use them. PARTICULARLY on the front-end. MORE so with HTML/CSS/JS where they are mind-numbingly idiotic halfwit garbage that no sane developer would use by choice; resulting in writing two to ten times the HTML needed to do the job, pissing on semantics, failing to maintain separation of presentation from content, and in general missing the entire POINT of HTML. Then people have the unmitigated gall to call more markup and specificity hell "easier"? BULLCOOKIES!
Server-side frameworks aren't much better; but then most of them rarely work on problems the way I think about solutions, so they are incompatible with my methodologies.
As I often say:
For people who know nothing about websites, BY people who know nothing about websites is NOT a plan for success.
Which even the bloody examples in the first few pages of react's tutorial quite clearly illustrates.
Though it's probably fine if you're the type vomiting up HTML with CtCR's of 10:1 (code to content ratio) instead of 2:1 or less thanks to endless pointless DIV for nothing, endless pointless classes for nothing, and a general ignorance of how to leverage CSS selectors and semantic markup properly.