That's really only half a question. What are the project requirements?

Are you making a website? a web app? What kind of data will you be displaying? How frequently does it change? Is the site highly customized per user or does everyone see basically the same content?

With Express/React you can choose both at the same time. When a user opens a page it renders on the server side and after that begins working as an SPA. The best of the two approaches.