Before ES6, I was on the CoffeeScript road.
I voted ES6 since it's going to be a standard anyway in the future -- however, out of curiosity: why not TypeScript?
Why not ES5 as an option? ES6 support is still weird and requires adding transpilation to your pipeline. Coffeescript also means transpiliation, and also means using a small niche of JS tools available.
Charles Zamoresen
Roc
Matan Yedayev
Full stack developer
I voted ES6, but actually - go for TypeScript.