As I have non-24 sleep-wake disorder -- resulting in living a 26 hour day -- the concept of a weekend, or even a normal 9 to 5 job are utterly incompatible with my lifestyle.
I HAVE to sleep an extra hour a day, and be awake an extra hour a day, or by body and mind goes haywire. As such the idea of a 7 day week doesn't entirely fly... it means I can't maintain the normal work schedule which is why I freelance -- and why I relax when I need to relax, and work when I need to work, and don't really have a fixed "well these days are for work and these days are for rest" as part of how I live.